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Considering treatment

For some people deciding to do treatment is not always an easy decision. There are a lot of factors to be considered. Perhaps the main concern with HCV treatment is the adverse effects that can be caused by the pharmaceutical drugs used in its treatment.

Making this decision can also raise other questions and issues. Some people might have strong views about the pharmaceutical industry or about putting chemicals in their bodies that do not occur naturally. But for the time being it may help to try to put any prejudices aside and to concentrate on the pros and cons of treatment itself:

The ‘pros’ of doing treatment

The major advantage which treatment offers you is that it’s the only ‘proven’ way of clearing the virus. People have undoubtedly cleared the virus in other ways, but only in very small numbers. So far there has been no other way that has been shown to work more consistently than interferon and ribavirin.

Treatment has also been shown to improve the health of the liver by reducing inflammation. It may also be able to reverse fibrosis or even cirrhosis. Although less often, this can also happen even in people who do not clear the virus.

Aside from health, there may be other benefits from clearing the virus. One of these could be financial. You should find that any insurance connected with your health becomes significantly cheaper. This could make an important difference to your mortgage.

If hepatitis C has made you incapable of working, once the virus has been cleared you may find you can go back to work. Knowing that you are no longer carrying an infectious and harmful virus may also help you to feel better about yourself.

If you are a woman, there is a small risk of passing hepatitis C to any child you give birth to. Clearing the virus would remove that risk.

If treatment is successful then you no longer risk infecting other people, through such ways as sharing a toothbrush or razor.

The 'cons' of doing treatment

The major disadvantage to treatment consists of the side effects. Not everyone necessarily experiences them. There are things you can do to keep them to a minimum but it’s possible that you may feel quite unwell some of the time. It can take a few months after the treatment ends before the drugs are cleared from your system. Ribavirin can take up to 6 months to clear. This could impact on your work (you might have to take time off), on your relationships, and on your social life. This might mean you have to tell people that you are doing treatment and therefore that you have hepatitis C.

Occasionally, the side effects can be so severe that they could force you to abandon treatment. You could be left with an illness after you stop treatment, such as thyroid disease or diabetes.

There is also the possibility that treatment might not work for you
Some people have reported that the side effects have persisted, leaving them feeling unwell long after the end of treatment.

These are the general pros and cons. On top of these your own individual circumstances will also have an important bearing. Some of these you may want to take into account are:

  • What are your priorities? Is clearing the virus your top priority?
  • What are your individual chances of clearing the virus? This will be most dependent on your genotype. Roughly, you have a 50% chance if you are genotype 1, or 70% if you are taking one of the new protease inhibitors, and an 80% chance if you are genotype 2 or 3.
  • How long will you need to do treatment for? If you are genotype 2 or 3, it will only last 24 weeks. If you are any other genotype (or if you have other complications) it will last 48 weeks, which is almost a year. This makes a difference.
  • Are you prepared or able to wait for the possibility of better drugs? If you have compensated cirrhosis, for example, can you risk it de-compensating before new drugs become available?
  • Will you be able to deal with any side effects? If they are particularly difficult will you be able to get the support you need?
  • Will you be able to plan your life around treatment? Can you be available for hospital visits, which are fairly frequent? Can you take time off work or other responsibilities if you have to?
  • Are you thinking of conceiving a child in the next year? (You should not conceive, as either a man or a woman, during treatment or for at least 6 months afterwards).

The best way to come to the right decision is to be equipped with the right information. The following sections about conventional treatment are intended to help you to do that. Please take the time to read through them.

Once you are informed, discuss it with your doctor. The idea behind medicine in the 21st century is that you and your doctor should work in partnership to improve your health. We are no longer in the era where the patient obediently does whatever the doctor says.

It is important to remember that deciding whether or not to do treatment is not clear-cut or easy. If anyone suggests otherwise, this may be because they have an agenda that is different from yours. This could include your doctor. If they really push you towards a decision arm yourself with the facts and ask then why.